Must-Know Facts About Starting and Stopping Depo-Provera

Depo-Provera (Medroxyprogesterone) is an injectable contraceptive method. It is very effective in preventing pregnancy. Depo-Provera contains progestogen, a synthetic progestin.

Many people are satisfied with Depo-Provera.Only four times a year It is more convenient than taking medicine every day. Because it is estrogen-free, you can even start using Depo while breastfeeding.

This article discusses what happens when you start Depo-Provera. It also discusses common side effects and what happens when you stop using this form of birth control.

Before starting Depo-Provera

Before you get your first Depo-Provera injection, you will need to be checked by your doctor. Your doctor will also review your health history. This is because Depo-Provera is a hormonal method of birth control. Hormonal contraception is not for everyone.

The manufacturer of Depo-Provera recommends the following tests:

  • blood pressure check
  • breast examination
  • abdominal examination
  • pelvic exam
  • Pap smear
  • blood tests, if relevant

Start Depo-Provera

You should take your first Depo-Provera injection five days before your period. This ensures that you are not pregnant at the time of the injection. If you are vaccinated at any other time in your cycle, you should have a pregnancy test first.

Depo-Provera provides immediate pregnancy protection if you get your first dose within the first five days of your period. You don’t need to use a backup birth control method.


Before starting Depo-Provera, you will need a medical examination. You should get your first shot five days before your period. This will ensure immediate protection of the pregnancy.

Side Effects of Depo-Provera

It is important to discuss potential side effects with your doctor before starting Depo-Provera.


Some people experience irregular or prolonged bleeding while using Depo-Provera. Others will not have any bleeding problems.

Spotting and persistent bleeding are the main reasons people stop taking Depo-Provera. People using Depo-Provera were more likely to stick with it if they were told about this potential side effect before their first injection.

There is no way to know in advance if you will have irregular bleeding or spotting. Bleeding may continue until the progesterone wears off. This can take up to 11 to 14 weeks after you stop the injections.

Studies show that about 50% of people who use Depo-Provera continuously for a year will stop all bleeding. This includes regular monthly bleeding. With continued use, this number rose to 70%.

loss of bone density

Depo-Provera may cause loss of bone mineral density. This leads to thinning of the bones and a high risk of fractures. Research suggests this may reverse when you stop taking Depo-Provera injections.

Try to maintain a healthy lifestyle while using Depo-Provera. This can help offset possible calcium loss from the bones.

Make sure you get enough calcium. Do weight-bearing and muscle-strengthening exercises. Avoid smoking and moderate alcohol consumption, or no alcohol at all.

weight gain

Some people gain weight after starting Depo-Provera. Before receiving your first injection, discuss diet and exercise with your doctor. Eating a healthy diet and exercising regularly may help reduce weight gain.


Depression affects about 9% of people who use this form of birth control. Before starting Depo-Provera, discuss this possible side effect with your doctor.


Depo-Provera may cause side effects such as long-term bleeding and weight gain. These side effects are the reason many people stop using Depo-Provera. More serious side effects may also occur.

Stop Depo-Provera

You can stop using Depo-Provera at any time, just don’t take the next photo.

Because Depo-Provera may cause a decrease in bone density, you should not use it for more than two years. Discuss other birth control options with your doctor at that time.

Pregnancy after Depo-Provera

Each Depo-Provera injection lasts about three months. If you decide to become pregnant after stopping Depo-Provera, you will need to plan ahead.

After stopping Depo-Provera, it takes an average of 7 to 10 months to regain fertility and start ovulation. Ovulation is when you release an egg every month and are able to conceive. Rarely, it may take up to 18 months.

Fertility may return once your last Depo injection is over. However, for most people, getting pregnant after Depo-Provera takes time.

You should stop getting Depo injections about a year before you want to get pregnant.


Depo-Provera is an injectable contraceptive method. Take it four times a year. Before starting Depo-Provera, it is important to perform a health check.

Side effects of this form of birth control include weight gain and prolonged bleeding or bleeding time. These are some of the reasons why people stop using Depo-Provera. However, in most cases, the bleeding will stop after a year.

Stop using Depo-Provera one year before you want to become pregnant.

Frequently Asked Questions

  • What hormones are in Depo-Provera?

    The Depo-Provera shot contains a progestin called medroxyprogesterone.

  • When should you get a Depo-Provera lens?

    Depo-Provera is a contraceptive injection that is given every three months. When starting Depo-Provera, you should get your first shot five days before your period.

  • Will Depo-Provera stop your period?

    maybe. About half of all women who use Depo-Provera continuously for one year stop menstruating. However, in some women, Depo-Provera can cause irregular or prolonged bleeding. If you have continuous spotting or irregular bleeding during the Depo injection, it should subside within 11 to 14 weeks after the injection.

  • How can you tell if you are pregnant while having a Depo injection?

    Depo-Provera may cause missed periods. Although it is a very effective method of contraception, it has an estimated pregnancy rate of 6 per 100 users per year. If you’ve missed your period and want to know if you’re pregnant, taking a pregnancy test is the only way to be sure.

    Take a pregnancy test if you experience pregnancy symptoms such as breast tenderness and growth, fatigue, nausea, food aversion, and a frequent need to urinate. If positive, call your doctor’s office.