The enhancement strategy involves the use of a combination of drugs, rather than a single OCD drug. Enhancement therapy involves the use of a combination of drugs, rather than a single OCD drug, to get the maximum effect. For people who do not respond to standard obsessive-compulsive disorder medications, enhancement strategies may be particularly effective.
Why use enhancement
If you have obsessive-compulsive disorder, you may know that there are many treatment options. However, you may also know that not everyone responds to these treatments.
Despite the introduction of selective serotonin reuptake inhibitors (SSRI), such as Luvox (fluvoxamine), Prozac (fluoxetine), Paxil (paroxetine) and Zoloft (sertraline) and tricyclic antidepressants, For example, Anafranil (clomipramine) has taken a big step forward. In the treatment of obsessive-compulsive disorder, 40% to 60% of people will not respond adequately to these drugs.
As in other medical fields, psychiatrists are now exploring whether a combination of drugs to treat OCD, rather than a single drug, can provide more relief for more people.
Use antipsychotic drugs to enhance current treatment
Although antidepressants are the standard medical treatment for OCD, it has been suggested that adding antipsychotic drugs to the treatment plan may help improve OCD symptoms.why is that?
First, antipsychotic drugs such as Risperdal (risperidone), Zyprexa (olanzapine) or Seroquel (quetiapine) in addition to affecting serotonin, also affect the level of the neurotransmitter dopamine. Problems with the dopamine system are also related to obsessive-compulsive disorder.
In addition, some people with OCD may find it difficult to believe that their obsessions and/or compulsive behaviors are illogical or unreasonable.Failure to recognize that obsessions and/or compulsive behaviors are meaningless has proven to be a barrier to benefit from standard treatment. It has been suggested that antipsychotic drugs may help change this mode of thinking.
Is enhancement therapy effective?
In general, the available scientific evidence indicates that for adults whose OCD symptoms do not respond to standard treatment, the use of antipsychotic drugs may be useful as a potentiator, but further research is needed.of
However, you must remember that there are two types of antipsychotic drugs, each with its potential side effects. First-generation or “typical” antipsychotics often have side effects associated with abnormal movements, called extrapyramidal side effects, such as stiffness, tremor, sluggishness, irritability, and tardive dyskinesia, involving involuntary and involuntary movements in different parts of the body The controlled movements include the mouth and face. Tardive dyskinesia can sometimes be permanent.
Second-generation or “atypical” antipsychotics usually have a smaller risk of extrapyramidal side effects, but are more likely to cause metabolic problems such as weight gain, blood sugar and cholesterol.
In view of this, the potential benefits of using antipsychotics as an enhancement strategy to reduce OCD symptoms should outweigh the risks.
As with any medical treatment, the decision to add antipsychotics to your current treatment plan should be made in close cooperation with your family doctor or psychiatrist.
Obsessive-compulsive disorder discussion guide
Get our printable guide to help you ask the right questions the next time you see a doctor.
Be sure to communicate any changes you encounter while trying new medicines or changing medicines. Maintaining this open discussion between you and your doctor will ensure that he/she keeps your individual needs in mind as your treatment plan progresses.