What is bipolar disorder?

Agitated depression (AD) is a relatively serious clinical depression that combines the persistent sadness, pessimism, low energy, low or “empty” emotions of typical depression, as well as irritability, anxiety, irritability, excessive talking, Fidgeting, and/or outbursts of anger.

This mental health condition can also be referred to as monophasic, mixed state, mixed characteristics, mixed mania, depression with psychomotor agitation, or mixed-onset depression.


There are many types of depression, as a group of mental health disorders, affecting more than 264 million people of all ages worldwide.AD is a manifestation of depression.

The diagnosis is still somewhat controversial and inconsistent (for example, some clinicians prefer to use the diagnosis of depression with mixed characteristics or view it as part of bipolar disorder) because the characteristics of the disorder overlap with various other types of depression .

However, researchers and clinicians increasingly understand that depression, mania, and mental health generally exist in a range, which is why various names can be used to describe a person’s depression, and each person may not necessarily behave. Show all possible symptoms of the situation.

Generally speaking, patients with agitation depression experience the intense discomfort, lack of energy, hopelessness and indifference of typical depression, as well as the urge to act, which usually manifests as unstable behavior, insomnia, negative emotions, confusion of thoughts, and grumpy temper.

Although these symptoms may also appear in depression, these problems are more pronounced and lasting for those with agitated depression.

Learn more about the causes, risk factors, diagnosis, and treatment of irritable depression below.


As mentioned above, this mental health disorder may be called agitation depression, or it may be classified in another way by your mental health provider. However, the common signs and symptoms of this condition will include some typical symptoms of depression, such as:

  • Low mood or moodiness
  • fatigue
  • Feeling worthless, ashamed, empty or guilty
  • Insomnia or too much sleep
  • Lack of energy, motivation and interest in things that were previously of interest
  • Weight loss or gain and/or eating more or less than usual
  • pessimism
  • sad
  • Suicidal ideation or attempt
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If you or someone you love has suicidal thoughts, please call the National Suicide Prevention Lifeline at 1-800-273-8255 to get support and help from trained counsellors. If you or someone you love is in immediate danger, call 911.

For more mental health resources, please refer to our national helpline database.

In addition, people with agitated depression also experience the following signs and symptoms, which define their condition as “restlessness”:

  • anger
  • anxiety
  • Angry at little things
  • Over-complaining
  • Extremely irritable
  • Feel the need to lash out or take action
  • Fidgeting
  • Talk endlessly
  • Biting nails, twisting hands and/or scratching skin, clothing and/or hair
  • break out
  • Racing thoughts
  • Irritability, pacing or excessive exercise
  • Yelling

As mentioned above, everyone may have a unique combination of depression and agitation symptoms, which together manifest as agitation depression.


Agitated depression is diagnosed by your doctor, psychiatrist, and/or mental health provider. Before making a diagnosis, your doctor will check your symptoms and medical history.

As mentioned above, the diagnosis of this disease is not entirely simple because it overlaps with several types of depression. Sometimes, once the nuances of the condition are discovered in treatment, a person is first diagnosed with depression and then diagnosed with anxiety depression.

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Your mental health provider will carefully evaluate your condition by observing your emotions and behavior. They will also record your medical and mental health history and learn more about your experience in talk therapy in order to distinguish bipolar disorder from other possible problems (such as bipolar disorder).

For diagnosis, the symptoms of the condition exist for at least two weeks, and at least two physical and/or mental agitation symptoms are accompanied by typical depressive symptoms.

A key component of agitation depression is that, unlike other mental health conditions that alternate between restlessness, elation, and/or activity (such as bipolar disorder), the feelings and behaviors of restlessness remain constant with the onset of symptoms. Change. Frustrated. Compared with other types of depression, the symptoms of agitation are also more extreme and lasting.

Another aspect of agitation depression that mental health providers will assess and pay attention to is the propensity for substance use disorder, self-harm, and suicidal ideation.

It is important to know that people with this disease are more likely to engage in these harmful thoughts and behaviors.


Like many mental health conditions, the causes or triggers of agitated depression are complex and are thought to be caused by multiple factors, including genetics, brain chemistry, childhood trauma, emotional distress, environmental factors, coexisting mental health conditions, and other problems.

Some common risk factors and contributing factors to agitated depression include:

Generally, there may be multiple factors that contribute to the development of this disease. Sometimes, the reason may not be completely clear.

In addition, some medications used to treat depression may induce restless behavior in people taking these medications, leading to the development of agitated depression.

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The treatment plan for agitated depression is similar to the treatment plan for other types of depression, usually including talk therapy and medication. Cognitive behavioral therapy aims to help people identify and change negative or destructive thinking patterns, and is often used to treat this condition.

Antidepressants, mood stabilizers, and/or anxiolytics are also often used in combination with therapy. Please note that it may take time for the medicines (usually one to two months or more) to take effect-and find the right medicine for you in the correct dosage.

In more severe cases where other treatments are ineffective, electroconvulsive therapy can also be used.

Agitated depression can be difficult to treat, so even if your symptoms seem to improve and/or you are free from depression, it is important to stick to your prescribed treatment plan.


Know that through treatment, agitation depression can be effectively controlled. As mentioned above, consistent treatment is the best way to alleviate this situation.

Getting care early in your depressive episode also makes treatment more likely and effective.

In addition to treatment, you can work hard to transform and control your thoughts and actions. There are many strategies and skills to help you cope with this situation, including the following:

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Finding that you have anxious depression can be disturbing, but know that your diagnosis may be the beginning of getting help.

With proper treatment and continuous attention to mental health, you can regain and maintain control over your life and mental health.