What is compensatory hypogonadism?

compensatory hypogonadism is a subclinical form of late-onset hypogonadism, a condition in which the sex organs or gonads stop producing adequate levels of sex hormones. It is estimated to affect 9.4% of older men.

This condition appears to occur independently of obesity and may be characterized by symptoms of impotence and erectile dysfunction, or with few or no symptoms.

Over the past few years, researchers have begun to look more closely at subclinical endocrine disorders, such as compensated hypogonadism, as they have been found to be markers of poor health and may herald other, more serious conditions such as heart disease.

This article will discuss the symptoms and causes associated with compensated hypogonadism, how the disorder is diagnosed, and treatment options.

What is compensatory hypogonadism?

Compensated hypogonadism (CH) is also known as age-related testosterone deficiency.This is due to a malfunction testis (testicles) produce more of the male hormone testosterone.

Reproductive and general health in men depends on balanced levels of androgens (male sex hormones, such as testosterone) and other hormones, which are mainly produced by specialized testicular cells (ledig and Sertoli cell).

As we age, these testicular cells luteinization Hormone (LH), a pituitary The hormone that tells the testes to make testosterone. Often, people with CH have elevated levels of LH because LH is not being used effectively.

Androgens, including testosterone, have many important functions in the body, such as promoting muscle growth, stimulating wakefulness, and affecting cognitive function. This means that when CH develops, it can cause a wide range of symptoms.

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Symptoms of CH

The signs and symptoms that a patient with compensated hypogonadism may experience will depend on when the deficiency begins, how long it lasts, its severity, and whether the primary function of the testis is diminished.

Many people with CH have no obvious symptoms, while others experience one or more of the following symptoms:

  • erectile dysfunction
  • fatigue or lethargy
  • low sperm count
  • upset
  • decreased libido
  • sleep disorder
  • Decreased muscle mass and strength

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What causes compensatory hypogonadism?

The reasons why CH occurs are poorly understood, but some experts believe it may be related to a decline in overall health.

A recent study found that people with CH were more likely to have problems with mobility, lower cognitive function, poor nutrition, and depressed mood than people with normal hormone levels. Another study found a correlation between vitamin D deficiency and an increased risk of CH.

However, unlike other types of hypogonadism, CH was not associated with lifestyle risk factors, including obesity, smoking, or alcohol consumption.

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How to Diagnose CH

If you are struggling with symptoms of compensated hypogonadism, be sure to consult a healthcare provider. At your appointment, a health care professional will perform a physical examination to look for any abnormalities in your sexual organs. They will also order blood tests.

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A diagnosis of CH is based on blood tests that check your hormone levels. CH is characterized by normal testosterone levels and high levels of LH. According to the European Male Aging Study, CH is marked by normal serum testosterone levels of 10.5 nanomoles per liter (nmol/L), but serum LH values ​​higher than 9.4 international units per liter (IU/L).

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How to treat CH

Although some types of hypogonadism are treated with synthetic testosterone, there is currently no indication that testosterone therapy is of sufficient benefit in patients with compensated hypogonadism.

Your healthcare provider can help you weigh any potential benefits and risks of testosterone therapy (such as an increased risk of prostate cancer, although still controversial) based on your overall health and symptoms.

Instead, most CH management strategies include adopting healthy lifestyle habits, such as regular exercise, eating a nutritious diet, reducing stress, and getting enough sleep.

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Prognosis: long-term response to CH

Hypogonadism is a hallmark of poor health and an increased risk of death, so diagnosis should be taken seriously. You’ll need to work with your healthcare provider to develop strategies to improve your overall health.

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The European Study of Aging in Men found that participants with compensated hypogonadism were three times more likely to die than men without any type of hypogonadism after four years of prospective follow-up. CH patients are also nearly twice as likely to die as those with other types of hypogonadism, such as secondary hypogonadism, or hypogonadotropin Hypogonadism.

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generalize

Compensated hypogonadism is a subclinical deficiency of the male sex hormone testosterone. Mainly due to age-related factors. Symptoms that appear include erectile dysfunction, low mood, muscle wasting and fatigue. This condition can be diagnosed with hormone blood tests. Currently, there are no recommended treatments other than developing healthy habits, such as exercise, healthy eating, and managing stress levels.

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Compensated hypogonadism is fairly common, but it’s not an easy diagnosis. Not only is CH almost asymptomatic, but there are a number of factors associated with changing health in old age that can cause large fluctuations in testosterone levels.

Therefore, treatment options for CH are limited at best. While research has demonstrated some positive effects of testosterone therapy, the clinical significance of these findings remains open to question. The best option for dealing with CH is to take steps to improve your overall health. Go for a daily walk in the sun, cook a colorful, veggie-rich meal, or pick up a new hobby.